Antibody Responses in Ostriches after Vaccination with Oil-adjuvanted Razi Newcastle Disease Vaccine

Ostrich (Struthio camelus) is also among sensitive species from which NDV isolated and reported in Iran shows the significance of the disease as a potential problem for this growing industry. The first aim of this study was evaluation of the ostrich antibody response to different doses of ND oil-adjuvanted vaccine produced by Razi vaccine and serum research institute (RVSRI), Karaj, Iran. ?? of African black neck ostrich chicks in Five different treatments were used in this experiment. In three groups Razi vaccine was injected with ?, ??, and ?? doses, one group received ? doses of an oil-adjuvanted vaccine produced by another company, and a control non vaccinated group. All vaccinated groups received ? injections at the ages of ??, and ?? days. Blood samples were taken three times before each vaccination and also ?? days after the second vaccination. Results were suggestive of an increasing trend of seral antibody levels after first and second vaccination in all vaccinated groups measured by ELISA an HI. There was no significant difference between all four vaccinated groups. Comparison between non-vaccinated group with all vaccinated groups showed significant difference. According to the results, and regarding the volume of the inoculums, the present study suggests the ?-dose in first vaccination at the age of ?-? weeks and the ??-dose in repeating vaccinations thereafter in higher ages.