A histopathology study of testis after experimentally induced varicocele in dog

Authors
Heidar Heidari Khoei
Azarnush Karimi
Hossein Hassanpour
Amin Bigham Sadegh
Iraj Karimi
Abstract
Varicocele is a pathological dilatation of the venous pampiniform plexus, found in the male spermatic cord, and a common condition, found in men who present for infertility evaluation. The purpose of this investigation was to create a simple and new method of varicocele model in dog and to study subsequent alterations in testicular histopathology. Six young adult dogs were used. Dilation of the venous pampiniform plexus in dogs was achieved by partial occlusion of proximal part of pampiniform plexus without abdominal incision. At the end of experiment, dogs were castrated and testes were dissected and processed for microscope examinations. Johnsen scores and histological abnormalities were evaluated for each testis. There were significant different between the Johnsen scores in the normal and varicocele induced testes. There were severe histological abnormalities in the varicocele induced testes and slightly microscopic changes was showed in the normal testes. The current study demonstrated that partial occlution of proximal part of pampiniform plexus could induce varicocele in dog. Varicocele also showed changes in the normal testis.

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