بررسی ارتباط هورمون‌های تیروئیدی و چربی‌های سرم خون (کلسترول، تری‌گلیسیرید، لیپوپروتئین با چگالی بالا - کلسترول و لیپوپروتئین با چگالی پائین - کلسترول) در اسب‌های نژاد دره‌شوری، عرب و آمیخته

نوع مقاله : مقاله پژوهشی

نویسندگان
1 دانش‌آموخته دوره دکترای عمومی دامپزشکی، دانشکده دامپزشکی، دانشگاه شیراز، شیراز- ایران
2 گروه بهداشت و مدیریت دام، دانشکده دامپزشکی، دانشگاه شیراز، شیراز- ایران
3 گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه شیراز، شیراز- ایران
10.22034/ijvcs.2024.14469.1056
چکیده
به‌منظور بررسی غلظت هورمون‌های تیروئیدی T3، T4 و چربی‌های سرم خون (کلسترول، تری‌گلیسیرید، لیپوپروتئین با چگالی بالا - کلسترول و لیپوپروتئین با چگالی پائین - کلسترول) اسب‌های به‌ظاهر سالم در نژادهای مختلف و یافتن ارتباط احتمالی میان این پارامترها، این مطالعه بر روی ۵۰ رأس اسب متعلق به اسب‌داری‌های اطراف شیراز شامل ۱۵ رأس دره‌شوری، ۱۵ رأس عرب، 20 رأس آمیخته (خارجی، کرد و ترکمن) که 26 رأس بالغ و 24 رأس زیر سه سال سن دارند، انجام شد. ارزیابی و امتیازدهی نمرات وضعیت بدنی باتوجه‌به شش ناحیه مرجعِ بدن اسب و نمره ستیغ گردنی (Cresty neck score) صورت گرفت. نمونه‌های خون از ورید وداج گرفته شده و فوراً سرم آن‌ها جدا شده و در دمای ۲۰- درجه سانتی‌گراد نگهداری شدند. بر اساس نتایج به‌دست‌آمده در تحقیق حاضر تفاوت‌های معنی‌دار در میزان هورمون تری‌یدوتیرونین T3، در بین اسب‌های با نمره بدنی بالاتر از ۷ و کمتر از آن دیده شد. همچنین تفاوت معنی‌داری در غلظت هورمون تیروکسین سرمی اسب‌ها در سنین مختلف دیده شد (005/0=P). در میان نژادهای مختلف، تفاوت معنی­داری در غلظت LDL سرم اسب‌ها وجود داشت که بیانگر متفاوت‌بودن میزان LDL در نژادهای مختلف در این پژوهش است (009/0=P)؛ اما هیچ تفاوت معنی‌داری در تمام پارامترهای تحت مطالعه با بررسی جنسیت، وضعیت‌های مختلف فیزیولوژیک و وضعیت نمره ستیغ گردنی دیده نشد. همبستگی‌های معنی‌داری میان کلسترول تام و تری‌گلیسیرید (۶۰۰/۰r=)، کلسترول تام و  LDL (۸۵۳/۰=r)، کلسترول تام و VLDL (۶۰۰/۰r=)، تری‌گلیسیرید و LDL (۵۲۱/r=۰)، LDL و VLDL(۵۲۱/۰r=)، هورمون تری‌یدوتیرونین و هورمون تیروکسین (۵۹۹/r=۰) وجود داشت (01/0>P). در این پژوهش، اسب‌های با نمره بدنی پایین‌تر، میزان هورمون تری‌یدوتیرونین بیشتری در سرم دارند. در میان نژادهای مختلف، تفاوت معنی­داری در غلظت LDL سرم اسب‌ها دیده شد.
کلیدواژه‌ها
موضوعات

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